mRNA-TNFSF11

Cat.#	Gene	Scale	State
LS-RMAbt-113	mRNA-TNFSF11	1mg	Lyophilized/Liquid

Cat.# Gene Scale State

LS-RMAbt-113 mRNA-TNFSF11 1mg Lyophilized/Liquid
Product Overview

mRNA-TNFSF11 is an in vitro transcribed (IVT) messenger RNA encoding tumor necrosis factor ligand superfamily member 11 (TNFSF11, also known as RANKL), a key cytokine that regulates osteoclast differentiation and activation through binding to RANK receptor. This synthetic mRNA enables controlled expression of RANKL for research in bone remodeling, cancer-induced osteolysis (e.g., breast cancer bone metastases), and development of RANKL-targeted therapies (e.g., denosumab analogs) for osteoporosis and bone-related malignancies.

Product Details

Storage Buffer: ddH₂O ph=7.0

mRNA length: 1251 nt

Amino acid sequence size: 317 aa

Handling and Storage: store at – 80℃ for long term
Amino acid sequence

MRRASRDYTKYLRGSEEMGGGPGAPHEGPLHAPPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFFYFRAQMDPNRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID
Storage & Logistic

Storage Conditions: 2°C to 8°C, protect from light

Shipping Conditions: Ambient

Expiration Date of Liquid Product: 12 Months

Retest Date of Powder Product: 18 Months