mRNA-TIGIT

Cat.#	Gene	Scale	State
LS-RMAbt-061	mRNA-TIGIT	1mg	Lyophilized/Liquid

Cat.# Gene Scale State

LS-RMAbt-061 mRNA-TIGIT 1mg Lyophilized/Liquid
Product Overview

mRNA-TIGIT is an in vitro transcribed (IVT) messenger RNA product that encodes the human TIGIT protein (T cell immunoreceptor with Ig and ITIM domains). TIGIT is an inhibitory immune checkpoint molecule expressed on the surface of immune cells such as T cells and natural killer (NK) cells. By binding to its ligands (such as CD155), TIGIT suppresses T cell proliferation, cytotoxic responses, and the secretion of inflammatory cytokines, thereby contributing to immunosuppression within the tumor microenvironment.

Product Details

Storage Buffer: ddH₂O ph=7.0

mRNA length: 1032 nt

Amino acid sequence size: 244 aa

Handling and Storage: store at – 80℃ for long term
Amino acid sequence

MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLRRKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFFTETG
Cell Expression Result

Cell Line: A549
Culture Plate: 96-well plate
Cell Confluency: 80%
Transfection Dose: 200 ng per well
Storage & Logistic

Storage Conditions: 2°C to 8°C, protect from light

Shipping Conditions: Ambient

Expiration Date of Liquid Product: 12 Months

Retest Date of Powder Product: 18 Months