mRNA-SIRPA

Cat.#	Gene	Scale	State
LS-RMAbt-088	mRNA-SIRPA	1mg	Lyophilized/Liquid

Cat.# Gene Scale State

LS-RMAbt-088 mRNA-SIRPA 1mg Lyophilized/Liquid
Product Overview

mRNA-SIRPA is an in vitro transcribed (IVT) messenger RNA encoding the signal regulatory protein alpha (SIRPα), a transmembrane glycoprotein that serves as a key inhibitory receptor on myeloid cells by binding to CD47 to mediate "don't eat me" signals. This synthetic mRNA enables controlled expression of SIRPα for research in phagocytosis regulation, tumor immune evasion mechanisms, and development of CD47/SIRPα-targeted cancer immunotherapies.

Product Details

Storage Buffer: ddH₂O ph=7.0

mRNA length: 1779 nt

Amino acid sequence size: 493 aa

Handling and Storage: store at – 80℃ for long term
Amino acid sequence

MEAPAQLLFLLLLWLPDTTGEEELQVIQPDKSVSVAAGESAILHCTVTSLIPVGPIQWFRGAGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNITPADAGTYYCVKFRKGSPDTEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREITQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK
Storage & Logistic

Storage Conditions: 2°C to 8°C, protect from light

Shipping Conditions: Ambient

Expiration Date of Liquid Product: 12 Months

Retest Date of Powder Product: 18 Months