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mRNA-PCSK9

Cat.# Gene Scale State
LS-RMAbt-045 mRNA-PCSK9 1mg Lyophilized/Liquid
  • Description
  • Product Overview
  • Sequence
  • Data Chart
  • Storage & Logistic
  • Documents
  • Cat.# Gene Scale State
    LS-RMAbt-045 mRNA-PCSK9 1mg Lyophilized/Liquid
  • Product Overview

    mRNA-PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) is a ready-to-use mRNA product encoding the PCSK9 protein. It is suitable for research on cholesterol metabolism, cardiovascular diseases, and targeted drug development. PCSK9 regulates the degradation of low-density lipoprotein receptors (LDLR), thereby influencing blood levels of low-density lipoprotein cholesterol (LDL-C). It is a key therapeutic target for lipid-lowering drugs such as Alirocumab and Evolocumab.

    Product Details

    Storage Buffer: ddH2O ph=7.0

    mRNA length: 2376 nt

    Amino acid sequence size: 692 aa

    Handling and Storage: store at – 80℃ for long term

  • Amino acid sequence

    MGTVSSRRSWWPLPLLLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLAEAPEHGTTATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTKILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAIARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAEASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEEAVTAVAICCRSRHLAQASQELQ

  • Storage & Logistic

    Storage Conditions: 2°C to 8°C, protect from light

    Shipping Conditions: Ambient

    Expiration Date of Liquid Product: 12 Months

    Retest Date of Powder Product: 18 Months

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