- Description
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- Sequence
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- Documents
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Cat.# Gene Scale State LS-RMAbt-099 mRNA—LRRC15 1mg Lyophilized/Liquid -
Product Overview
mRNA-LRRC15 is an in vitro transcribed (IVT) messenger RNA encoding the leucine-rich repeat-containing protein 15 (LRRC15), a transmembrane protein that serves as a marker of cancer-associated fibroblasts (CAFs) and regulates TGF-β signaling in the tumor microenvironment. This synthetic mRNA enables controlled expression of LRRC15 for research in solid tumor stroma interactions, fibroblast-immune cell crosstalk, and development of LRRC15-targeted therapies (e.g., CAR-T cells) against fibrotic cancers like pancreatic ductal adenocarcinoma and glioblastoma.
Product Details
Storage Buffer: ddH2O ph=7.0
mRNA length: 2043 nt
Amino acid sequence size: 581 aa
Handling and Storage: store at - 80 ℃ for long term
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Amino acid sequence
MPLKHYLLLLVGCQAWGAGLAYHGCPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVRGQSLIIINVNVAVPSVHVPEVPSYPETPWYPDTPSYPDTTSVSSTTELTSPVEDYTDLTTIQVTDDRSVWGMTQAQSGLAIAAIVIGIVALACSLAACVGCCCCKKRSQAVLMQMKAPNEC
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Storage & Logistic
Storage Conditions: 2°C to 8°C, protect from light
Shipping Conditions: Ambient
Expiration Date of Liquid Product: 12 Months
Retest Date of Powder Product: 18 Months
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