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Cat.# Gene Scale State LS-RMAbt-105 mRNA-FCAR 1mg Lyophilized/Liquid -
Product Overview
mRNA-FCAR (CD89) is an in vitro transcribed (IVT) messenger RNA encoding the Fc alpha receptor (FCAR/CD89), the primary receptor for IgA antibodies that mediates phagocytosis, antibody-dependent cellular cytotoxicity (ADCC), and inflammatory responses in myeloid cells. This synthetic mRNA enables controlled expression of CD89 for research in mucosal immunity, bacterial/viral pathogenesis (e.g., Streptococcus pneumoniae, HIV), and development of IgA-based immunotherapies targeting CD89+ immune cells in cancers and autoimmune diseases.
Product Details
Storage Buffer: ddH2O ph=7.0
mRNA length: 1161 nt
Amino acid sequence size: 287 aa
Handling and Storage: store at – 80℃ for long term
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Amino acid sequence
MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK
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Storage & Logistic
Storage Conditions: 2°C to 8°C, protect from light
Shipping Conditions: Ambient
Expiration Date of Liquid Product: 12 Months
Retest Date of Powder Product: 18 Months
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