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mRNA-ANGPTL3

Cat.# Gene Scale State
LS-RMAbt-111 mRNA-ANGPTL3 1mg Lyophilized/Liquid
  • Description
  • Product Overview
  • Sequence
  • Data Chart
  • Storage & Logistic
  • Documents
  • Cat.# Gene Scale State
    LS-RMAbt-111 mRNA-ANGPTL3 1mg Lyophilized/Liquid
  • Product Overview

    mRNA-ANGPTL3 is an in vitro transcribed (IVT) messenger RNA encoding angiopoietin-like protein 3 (ANGPTL3), a hepatocyte-secreted glycoprotein that regulates lipid metabolism by inhibiting lipoprotein lipase (LPL) and endothelial lipase (EL) activity. This synthetic mRNA enables controlled expression of ANGPTL3 for research in dyslipidemia mechanisms, cardiovascular disease models, and development of ANGPTL3-targeted therapies (e.g., monoclonal antibodies or gene silencing approaches) for treating hypertriglyceridemia and atherosclerosis.

    Product Details

    Storage Buffer: ddH2O ph=7.0

    mRNA length: 1680 nt

    Amino acid sequence size: 460 aa

    Handling and Storage: store at – 80℃ for long term

  • Amino acid sequence

    MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGN HETNYTLHLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDEC GENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE

  • Storage & Logistic

    Storage Conditions: 2°C to 8°C, protect from light

    Shipping Conditions: Ambient

    Expiration Date of Liquid Product: 12 Months

    Retest Date of Powder Product: 18 Months

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